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Dr S Melamane

Lecturer (Pharmaceutics)
siyabonga.melamane@ru.ac.za
046 603 8668

Qualifications:
PhD (Pharmaceutics, RU), MSc (Pharmaceutics, RU), BPharm (RU)

Teaching:

  • Applied Physical Pharmaceutics (Interfacial Phenomena, Surfactants, Colloids, Suspensions and Emulsions)
  • Micromeritics
  • Rheology
  • Solutions and suspensions
  • Topical delivery systems
  • Pharmaceutical Calculations
  • Nasal delivery systems

Research Interests:

  • Intranasal route for direct-to-brain delivery
  • Preformulation studies
  • Pharmaceutical formulation development and optimization (in-situ thermo-sensitive hydrogels, nano-emulsions and nanomicellar solutions)
  • Artificial neural networks

Selected publications:

  • Melamane S et al. Artificial neural network-based inference of drug target interactions, Nanotechnology Principles in Drug Targeting and Diagnosis, 2023
  • Witika BA et al. Lipid-Based Nanocarriers for Neurological Disorders: A Review of the State-of-the-Art and Therapeutic Success to Date, Pharmaceutics, 14 (4), 2022
  • Melamane S, Khamanga SMM, Walker RB. Formulation optimization of smart thermosetting lamotrigine loaded hydrogels using response surface methodology, Box Behnken design and artificial neural networks, Drug Development and Industrial Pharmacy, 46 (9), 2020